Melanodermia? Pigmentary Morphœa

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Pigmentary Disorders

Many factors have been implicated for the etiology of melasma, but the exact cause of this hypermelanosis is poorly understood. However, it is considered to result from solar radiation and genetic predisposition. Moreover, pregnancy, oral contraception and hormone replacement therapy with natural and synthetic oestrogens, have been involved in the pathogenesis of this hypemelanosis. Despite the...

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Genetics of pigmentary disorders.

The genetic and molecular bases of various types of congenital pigmentary disorders have been classified in the past 10 years, as follows: (1) disorders of melanoblast migration in the embryo from the neural crest to the skin: piebaldism; Waardenburg syndrome 1-4 (WS1-WS4); dyschromatosis symmetrica hereditaria. (2) Disorders of melanosome formation in the melanocyte: Hermansky-Pudlak syndrome ...

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A Peculiar Pigmentary Condition

History.?In October 1910, the patient, Sepoy T. K., 27th Punjabis, showed me some pigmented spots on iiis face, hands and left leg. They first appeared in March, 1U0S, when the patient was living in Jhandola. He believed that quinine, which he was taking prophylactically at that time, caused their appearance. No fresh spots have appeared since then, but some of the original areas have increased...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1939

ISSN: 0035-9157

DOI: 10.1177/003591573903200509